ITD-1(ITD1) TGFβ受体抑制剂|CAS 1099644-42-4

ITD-1(ITD1) TGFβ受体抑制剂|CAS 1099644-42-4

产品说明书

FAQ

COA

已发表文献

 

ITD-1 (ITD1)是选择性的TGFβ体抑制剂,IC50460 nM,通过将TGFBR2转移至蛋白酶体降解,抑制TGFβ信号。ITD-1选择性地增强未定型中胚层向心肌细胞的分化,但不增强向血管平滑肌和内皮细胞的分化。ITD-1具有潜在价值,不仅可用于研究ESC分化,还可用于探索TGFβ信号在癌症、纤维化或成人心血管疾病等病理过程中的作用。

 

产品性质

英文别名 (English Synonym)

ITD-1, ITD1

中文名称 (Chinese Name)

4-[1,1'-联苯]-4--1,4,5,6,7,8-六氢-2,7,7-三甲基-5-氧代-3-喹啉羧酸乙酯

靶点 (Target)

TGFβ receptor

通路 (Pathway)

TGF-β/Smad–TGF-β Receptor

CAS (CAS NO.)

1099644-42-4

分子式 (Formula)

C27H29NO3

分子量 (Molecular Weight)

415.52

外观 (Appearance)

粉末

纯度 (Purity)

≥98%

溶解性 (Solubility)

DMSO

结构式 (Structure)

ITD-1(ITD1) TGFβ受体抑制剂|CAS 1099644-42-4

 

运输和保存方法

冰袋运输。粉末直接保存于-20℃,有效期3年。建议分装后-20℃干燥保存,避免反复冻融。

 

注意事项

1. 为了您的安全和健康,请穿实验服并戴一次性手套操作。

2. 粉末溶解前请先短暂离心,以保证产品全在管底。

3. 请勿吸入吞咽或者直接接触皮肤和眼睛

4. 本产品仅用于科研用途,禁止用于人身上。

 

使用浓度

【具体使用浓度请参考相关文献,并根据自身实验条件(如实验目的,细胞种类,培养特性等)进行摸索和优化。

 

使用方法(数据来自于公开发表的文献,仅供参考)

细胞实验(体外实验)

ITD-1有效阻断TGFβ2诱导的SMAD2/3蛋白磷酸化,仅对Activin A无明显影响ITD-1选择性地增强未定型中胚层向心肌细胞的分化,但不增强血管平滑肌和内皮细胞的分化。[1] 

 

参考文献

1.Willems E, et al. Small molecule-mediated TGF-β type II receptor degradation promotes cardiomyogenesis in embryonic stem cells. Cell Stem Cell. 2012 Aug 3;11(2):242-52.

HB221117

ITD-1(ITD1) TGFβ受体抑制剂|CAS 1099644-42-4

暂无内容

ITD-1(ITD1) TGFβ受体抑制剂|CAS 1099644-42-4

暂无内容

 

ITD-1 (ITD1)是选择性的TGFβ体抑制剂,IC50460 nM,通过将TGFBR2转移至蛋白酶体降解,抑制TGFβ信号。ITD-1选择性地增强未定型中胚层向心肌细胞的分化,但不增强向血管平滑肌和内皮细胞的分化。ITD-1具有潜在价值,不仅可用于研究ESC分化,还可用于探索TGFβ信号在癌症、纤维化或成人心血管疾病等病理过程中的作用。

 

产品性质

英文别名 (English Synonym)

ITD-1, ITD1

中文名称 (Chinese Name)

4-[1,1'-联苯]-4--1,4,5,6,7,8-六氢-2,7,7-三甲基-5-氧代-3-喹啉羧酸乙酯

靶点 (Target)

TGFβ receptor

通路 (Pathway)

TGF-β/Smad–TGF-β Receptor

CAS (CAS NO.)

1099644-42-4

分子式 (Formula)

C27H29NO3

分子量 (Molecular Weight)

415.52

外观 (Appearance)

粉末

纯度 (Purity)

≥98%

溶解性 (Solubility)

DMSO

结构式 (Structure)

ITD-1(ITD1) TGFβ受体抑制剂|CAS 1099644-42-4

 

运输和保存方法

冰袋运输。粉末直接保存于-20℃,有效期3年。建议分装后-20℃干燥保存,避免反复冻融。

 

注意事项

1. 为了您的安全和健康,请穿实验服并戴一次性手套操作。

2. 粉末溶解前请先短暂离心,以保证产品全在管底。

3. 请勿吸入吞咽或者直接接触皮肤和眼睛

4. 本产品仅用于科研用途,禁止用于人身上。

 

使用浓度

【具体使用浓度请参考相关文献,并根据自身实验条件(如实验目的,细胞种类,培养特性等)进行摸索和优化。

 

使用方法(数据来自于公开发表的文献,仅供参考)

细胞实验(体外实验)

ITD-1有效阻断TGFβ2诱导的SMAD2/3蛋白磷酸化,仅对Activin A无明显影响ITD-1选择性地增强未定型中胚层向心肌细胞的分化,但不增强血管平滑肌和内皮细胞的分化。[1] 

 

参考文献

1.Willems E, et al. Small molecule-mediated TGF-β type II receptor degradation promotes cardiomyogenesis in embryonic stem cells. Cell Stem Cell. 2012 Aug 3;11(2):242-52.

HB221117

ITD-1(ITD1) TGFβ受体抑制剂|CAS 1099644-42-4

暂无内容

ITD-1(ITD1) TGFβ受体抑制剂|CAS 1099644-42-4

暂无内容

Human TGF-β2 重组人转化生长因子β2(人TGF-β2)

Human TGF-β2 重组人转化生长因子β2(人TGF-β2)

产品说明书

FAQ

COA

已发表文献

TGF-beta 2 (transforming growth factor beta 2) is one of three closely related mammalian members of the large TGF-beta  superfamily that share a characteristic cysteine knot structure. TGF-beta 1, -2 and -3 are highly pleiotropic cytokines proposed to act as cellular switches that regulate processes such as immune function, proliferation and epithelial-mesenchymal transition. Each TGF-beta isoform has some non-redundant functions; for TGF-beta 2, mice with targeted deletion show defects in development of cardiac, lung, craniofacial, limb, eye, ear and urogenital systems . Human TGF-beta 2 cDNA encodes a 414 amino acid (aa) precursor that contains a 19 aa signal peptide and a 395 aa proprotein. A furin-like convertase processes the proprotein to generate an N-terminal 232 aa latency-associated peptide (LAP) and a C-terminal 112 aa mature TGF-  beta 2. Disulfide-linked homodimers of LAP and TGF-beta 2 remain non-covalently associated after secretion, forming the small latent TGF-beta 1 complex. Covalent linkage of LAP to one of three latent TGF-beta binding proteins (LTBPs) creates a large latent complex that may interact with the extracellular matrix. Mature human TGF-beta 2 shows 100% aa identity with porcine, canine, equine and bovine TGF-beta 2, and 97% aa identity with mouse and rat TGF-beta 2. It demonstrates cross-species activity.

 

Product Properties

Synonyms

Transforming Growth Factor beta 2

Accession

P61812

Gene ID

7042

Source

NS0-derived Human TGF-β2 protein, Ala303Ser414 

Molecular Weight

Approximately 24 kDa.

AA Sequence

ALDAAYCF RNVQDNCCLR PLYIDFKRDL GWKWIHEPKG YNANFCAGAC PYLWSSDTQH SRVLSLYNTI NPEASASPCC VSQDLEPLTI LYYIGKTPKI EQLSNMIVKS CKCS

Tag

None

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Purity

> 97% as determined by SDS-PAGE.

Biological Activity

Measured by its ability to inhibit the IL-4-dependent proliferation of HT‑2 mouse T cells. The ED50 for this effect is 0.025-0.25 ng/mL.

Endotoxin

0.1 EU per 1μg of the protein by the LAL method.

Formulation

Lyophilized from 0.2 µm filtered concentrated solution in 35 % Acetonitrile and 0.1 % TFA.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile 4 mM HCl to a concentration of 0.1 mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriately buffered solutions.

 

Shipping and Storage

The products are shipped with ice pack and can be stored at –20 to -70 °C for 1 year.

Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.

 

Cautions 

1. Avoid repeated freeze-thaw cycles.

2. For your safety and health, please wear lab coats and disposable gloves for operation.

3. For research use only.

 

HB220903

 

Human TGF-β2 重组人转化生长因子β2(人TGF-β2)

暂无内容

Human TGF-β2 重组人转化生长因子β2(人TGF-β2)

暂无内容

TGF-beta 2 (transforming growth factor beta 2) is one of three closely related mammalian members of the large TGF-beta  superfamily that share a characteristic cysteine knot structure. TGF-beta 1, -2 and -3 are highly pleiotropic cytokines proposed to act as cellular switches that regulate processes such as immune function, proliferation and epithelial-mesenchymal transition. Each TGF-beta isoform has some non-redundant functions; for TGF-beta 2, mice with targeted deletion show defects in development of cardiac, lung, craniofacial, limb, eye, ear and urogenital systems . Human TGF-beta 2 cDNA encodes a 414 amino acid (aa) precursor that contains a 19 aa signal peptide and a 395 aa proprotein. A furin-like convertase processes the proprotein to generate an N-terminal 232 aa latency-associated peptide (LAP) and a C-terminal 112 aa mature TGF-  beta 2. Disulfide-linked homodimers of LAP and TGF-beta 2 remain non-covalently associated after secretion, forming the small latent TGF-beta 1 complex. Covalent linkage of LAP to one of three latent TGF-beta binding proteins (LTBPs) creates a large latent complex that may interact with the extracellular matrix. Mature human TGF-beta 2 shows 100% aa identity with porcine, canine, equine and bovine TGF-beta 2, and 97% aa identity with mouse and rat TGF-beta 2. It demonstrates cross-species activity.

 

Product Properties

Synonyms

Transforming Growth Factor beta 2

Accession

P61812

Gene ID

7042

Source

NS0-derived Human TGF-β2 protein, Ala303Ser414 

Molecular Weight

Approximately 24 kDa.

AA Sequence

ALDAAYCF RNVQDNCCLR PLYIDFKRDL GWKWIHEPKG YNANFCAGAC PYLWSSDTQH SRVLSLYNTI NPEASASPCC VSQDLEPLTI LYYIGKTPKI EQLSNMIVKS CKCS

Tag

None

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Purity

> 97% as determined by SDS-PAGE.

Biological Activity

Measured by its ability to inhibit the IL-4-dependent proliferation of HT‑2 mouse T cells. The ED50 for this effect is 0.025-0.25 ng/mL.

Endotoxin

0.1 EU per 1μg of the protein by the LAL method.

Formulation

Lyophilized from 0.2 µm filtered concentrated solution in 35 % Acetonitrile and 0.1 % TFA.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile 4 mM HCl to a concentration of 0.1 mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriately buffered solutions.

 

Shipping and Storage

The products are shipped with ice pack and can be stored at –20 to -70 °C for 1 year.

Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.

 

Cautions 

1. Avoid repeated freeze-thaw cycles.

2. For your safety and health, please wear lab coats and disposable gloves for operation.

3. For research use only.

 

HB220903

 

Human TGF-β2 重组人转化生长因子β2(人TGF-β2)

暂无内容

Human TGF-β2 重组人转化生长因子β2(人TGF-β2)

暂无内容

abbomax TGF beta说明书

 

AbboMax,Inc是一家以研究为导向,以客户为中心的抗体,多肽,化验产品和服务公司,致力于提供高的产品和服务质量以及高水平的客户满意度。

abbomax  TGF beta说明书

abbomax 500-3944

transforming growth factor, beta 3; TGFB3

TGF beta

转化生长因子,β3;TGFB3

TGF beta

转化生长因子,β3;TGFB3

目录 #: 500-3944
批号: 见标签
尺寸: 100 微克
主办: 兔子
分型: 兔IgG
应用范围: IHC(P),WB,IP
反应性: hu
价钱: $ 299.00

产品准备

源自人TGF-β蛋白C端的合成肽。

背景

不适用

纯化

兔IgG通过表位亲和纯化进行纯化

特殊性

该抗体识别〜13 kDa的TGF-β。它与人,大鼠和小鼠反应。其他物种未经测试。

公式

这种亲和纯化的抗体在含有抗体稳定剂的无菌磷酸盐缓冲盐水(pH7.2)中提供。

存储

当储存在–20oC时,抗体自收到之日起稳定12个月。抗体可以在2oC-8oC下保存一个月,而不会发现活性降低。避免重复冻融循环。

基因编号

5594

应用/建议的工作稀释度

蛋白质印迹

0.1-1微克/毫升

ELISA法

0.01-0.1微克/毫升

免疫沉淀

2-5微克/毫升

卫生组织

2-10微克/毫升

流式细胞仪

5-10微克/毫升

 

shenandoah TGF beta 1产品

 shenandoah TGF beta 1产品

Human TGF beta 1

 

人类TGF beta 1

转化生长因子β1(TGF-b1)是细胞因子TGF-β超家族的成员。该家族的成员在免疫,增殖,粘附,迁移和生长抑制途径中表现出调节活性。 

SKU 选择大小 价钱
100-39-5ug 迷你:5 ug $ 79.00
100-39-20ug 标准:20 ug $ 284.00
100-39-100ug 值:100 ug $ 1,045.00
100-39-500ug Midgi:500 ug $ 3,145.00
100-39-1毫克 镁:1毫克 $ 5,245.00

 

替代名称:  分化抑制因子,软骨诱导因子               登录号: P01137
说明:  转化生长因子β1(TGF-b1)是细胞因子TGF-beta超家族的成员。该家族的成员在免疫,增殖,粘附,迁移和生长抑制途径中表现出调节活性。TGF-b1通过TGF-bRI和TGF-bRII受体通过SMAD蛋白发出信号。除重组IL-2外,TGF-b1还经常用于在细胞培养中生产Treg细胞。  
来源:  转基因CHO细胞。
预测分子量: 二聚体,12.8 / 25.6 kDa(112/224 aa)
AA序列:  ALDTNYCFSS TEKNCCVRQL YIDFRKDLGW KWIHEPKGYH ANFCLGPCPY IWSLDTQYSK VLALYNQHNP GASAAPCCVP QALEPLPIVY YVGRKPKVEQ LSNMIVRSCK CS
配方:  从无菌(0.2微米)过滤水溶液中冻干至含有0.1%三氟已乙二醛(TF )的0.1%三氟已酸乙二醛(TFA)

产品规格* 
*每种产品的相应COA均提供以下特定规格的全部值。此处提供的值是通过内部要求的小期望值。 

规范

确定方法

验收标准

纯度

还原和非还原SDS PAGE

≥95%

内毒素

动能LAL

≤1EUs /微克

生物活性

抑制IL-4诱导的HT-2细胞增殖

≤500pg / mL

 ****参考单位: 人TFG-beta的活性为2.2 x 10 ^ 4 RU /μg,已针对重组人TGF-beta 1 NIBSC代码:89/514进行了校准。

准备和储存

原产国:美国       

运输:室温             

复原前的储存:-20°C

产品配制:0.1 mg / mL无菌10 mM HCl

说明:打开之前,先离心小瓶。通过将上述建议的溶液轻轻吸到小瓶的侧面来挂起产品。不要涡旋。等待几分钟,以完成重建。为了延长存储时间,请在0.1%BSA溶液中稀释至可工作的等分试样,然后在-80°C下存储,并避免重复冻融。

截止日期:      

  • 如果按提供的方式在-20°C至-80°C下存储,则从收到之日起12个月。
  • 按照指示重新配制后,在4°C下储存1个月。
  • 按照指示重新配制后,在-20°C至-80°C下储存3个月。

Human TGF-alpha 重组人转化生长因子α(人TGF-a)

Human TGF-alpha 重组人转化生长因子α(人TGF-a)

产品说明书

FAQ

COA

已发表文献

Transforming Growth Factor-alpha (TGF-α) , also known as sarcoma growth factor, TGF-type I and ETGF, is a member of the EGF family of cytokines.  TGF-α is an EGF-related polypeptide growth factor that signals through the EGF receptor, and stimulates the proliferation of a wide range of epidermal and epithelial cells.Mature TGF-alpha  shows approximately 93% amino acid sequence identity with mouse or rat TGF-alpha and is not species specific in its biological effects.

 

Product Properties

Synonyms

Transforming Growth Factor alpha; TGF-a; TGF-type I; ETGF

Accession

P01135

Gene ID

7039

Source

E.coli-derived Human TGF-a protein, Vla40-Ala89 

Molecular Weight

Approximately 5.8 kDa, on SDS-PAGE under reducing conditions.

AA Sequence

V VSHFNDCPDS HTQFCFHGTC RFLVQEDKPA CVCHSGYVGA RCEHADLLA

Tag

None

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Purity

> 95% as determined by SDS-PAGE

Biological Activity

Measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblast cells. The ED50 for this effect is < 0.4 ng/mL.

Endotoxin

1.0 EU per 1μg of the protein by the LAL method.

Formulation

Lyophilized after extensive dialysis against PBS.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O or PBS up to 100 μg/ml.For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.

 

Shipping and Storage

The products are shipped with ice pack and can be stored at 80 for 1 year from date of receipt.
1week, 2 to 8 °C under sterile conditions after reconstitution.
3 months, -20 °C under sterile conditions after reconstitution.

Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.

 

Cautions

1.For your safety and health, please wear lab coats and disposable gloves for operation.

2.For research use only!

HB230921

Human TGF-alpha 重组人转化生长因子α(人TGF-a)

暂无内容

Human TGF-alpha 重组人转化生长因子α(人TGF-a)

暂无内容

Transforming Growth Factor-alpha (TGF-α) , also known as sarcoma growth factor, TGF-type I and ETGF, is a member of the EGF family of cytokines.  TGF-α is an EGF-related polypeptide growth factor that signals through the EGF receptor, and stimulates the proliferation of a wide range of epidermal and epithelial cells.Mature TGF-alpha  shows approximately 93% amino acid sequence identity with mouse or rat TGF-alpha and is not species specific in its biological effects.

 

Product Properties

Synonyms

Transforming Growth Factor alpha; TGF-a; TGF-type I; ETGF

Accession

P01135

Gene ID

7039

Source

E.coli-derived Human TGF-a protein, Vla40-Ala89 

Molecular Weight

Approximately 5.8 kDa, on SDS-PAGE under reducing conditions.

AA Sequence

V VSHFNDCPDS HTQFCFHGTC RFLVQEDKPA CVCHSGYVGA RCEHADLLA

Tag

None

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Purity

> 95% as determined by SDS-PAGE

Biological Activity

Measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblast cells. The ED50 for this effect is < 0.4 ng/mL.

Endotoxin

1.0 EU per 1μg of the protein by the LAL method.

Formulation

Lyophilized after extensive dialysis against PBS.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O or PBS up to 100 μg/ml.For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.

 

Shipping and Storage

The products are shipped with ice pack and can be stored at 80 for 1 year from date of receipt.
1week, 2 to 8 °C under sterile conditions after reconstitution.
3 months, -20 °C under sterile conditions after reconstitution.

Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.

 

Cautions

1.For your safety and health, please wear lab coats and disposable gloves for operation.

2.For research use only!

HB230921

Human TGF-alpha 重组人转化生长因子α(人TGF-a)

暂无内容

Human TGF-alpha 重组人转化生长因子α(人TGF-a)

暂无内容

重组TGF-β1蛋白 重组转化生长因子-β1(人/鼠/小鼠TGF-β1)

重组TGF-β1蛋白 重组转化生长因子-β1(人/鼠/小鼠TGF-β1)

产品说明书

FAQ

COA

已发表文献

产品信息

产品名称

产品编号

规格

Recombinant Human/Mouse/Rat TGF-beta 1 Protein

91701ES05

2 μg

91701ES10

10 μg

91701ES60

100 μg

 

产品简介

转化生长因子-β1(TGFb1属于TGF-β 家族中,所占比例最高(>90%),活性最强的一种多功能细胞活性调节因子。重组人转化生长因子β1(TGF-β1)是一种用于细胞培养应用的生物活性蛋白,其是一种多功能肽,在许多细胞类型中控制增殖、分化和其他功能。TGF-β1的三种哺乳动物亚型,TGF-β1、β2和β3,通过相同的受体发出信号,并引发相似的生物反应。它们是多功能细胞因子,调节细胞增殖、生长、分化和运动,以及细胞外基质的合成和沉积,参与各种生理过程,包括胚胎发生、组织重塑和伤口愈合。在干细胞培养中,TGF-β1常与bFGF一起用于未分化的人类胚胎干 (ES) 细胞和诱导多能干 (iPS) 细胞的培养。

本品由HEK293细胞表达的,是一种25.0kDa的蛋白质,每个亚基含有112个氨基酸,通过单个二硫键连接,具有高活性、高纯度、无标签及低内毒素等特点。

 

性能参数

分子别名

CEDLAP, DPD1, latency-associated peptide, TGF beta, TGF beta1

Uniprot No.

P01137

表达系统及表达区间

HEK293-derived Human TGF-β1, Ala279Ser390.

标签

分子量

25kDa

纯度

> 95% as determined by SDS-PAGE.

生物活性

Measured by the (CAGA)12—luciferase reporter assay. The EC50 for this effect is 1.092 ng/mL.

内毒素

< 0.01 EU per 1μg of the protein by the LAL method.

制剂

在无菌PBS缓冲液中。

在打开小瓶之前对其进行离心该溶液可以稀释到其他水性缓冲液中。

产品形态

液体

 

储存条件

85~65℃保存,收到货之后有效期1年。建议首次使用时将蛋白等分,避免重复冻融循环。

 

注意事项

1. 本产品仅作科研用途

2. 为了您的安全和健康,请穿实验服并佩戴一次性手套操作。

Ver. CN20240305

 

重组TGF-β1蛋白 重组转化生长因子-β1(人/鼠/小鼠TGF-β1)

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重组TGF-β1蛋白 重组转化生长因子-β1(人/鼠/小鼠TGF-β1)

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产品信息

产品名称

产品编号

规格

Recombinant Human/Mouse/Rat TGF-beta 1 Protein

91701ES05

2 μg

91701ES10

10 μg

91701ES60

100 μg

 

产品简介

转化生长因子-β1(TGFb1属于TGF-β 家族中,所占比例最高(>90%),活性最强的一种多功能细胞活性调节因子。重组人转化生长因子β1(TGF-β1)是一种用于细胞培养应用的生物活性蛋白,其是一种多功能肽,在许多细胞类型中控制增殖、分化和其他功能。TGF-β1的三种哺乳动物亚型,TGF-β1、β2和β3,通过相同的受体发出信号,并引发相似的生物反应。它们是多功能细胞因子,调节细胞增殖、生长、分化和运动,以及细胞外基质的合成和沉积,参与各种生理过程,包括胚胎发生、组织重塑和伤口愈合。在干细胞培养中,TGF-β1常与bFGF一起用于未分化的人类胚胎干 (ES) 细胞和诱导多能干 (iPS) 细胞的培养。

本品由HEK293细胞表达的,是一种25.0kDa的蛋白质,每个亚基含有112个氨基酸,通过单个二硫键连接,具有高活性、高纯度、无标签及低内毒素等特点。

 

性能参数

分子别名

CEDLAP, DPD1, latency-associated peptide, TGF beta, TGF beta1

Uniprot No.

P01137

表达系统及表达区间

HEK293-derived Human TGF-β1, Ala279Ser390.

标签

分子量

25kDa

纯度

> 95% as determined by SDS-PAGE.

生物活性

Measured by the (CAGA)12—luciferase reporter assay. The EC50 for this effect is 1.092 ng/mL.

内毒素

< 0.01 EU per 1μg of the protein by the LAL method.

制剂

在无菌PBS缓冲液中。

在打开小瓶之前对其进行离心该溶液可以稀释到其他水性缓冲液中。

产品形态

液体

 

储存条件

85~65℃保存,收到货之后有效期1年。建议首次使用时将蛋白等分,避免重复冻融循环。

 

注意事项

1. 本产品仅作科研用途

2. 为了您的安全和健康,请穿实验服并佩戴一次性手套操作。

Ver. CN20240305

 

重组TGF-β1蛋白 重组转化生长因子-β1(人/鼠/小鼠TGF-β1)

暂无内容

重组TGF-β1蛋白 重组转化生长因子-β1(人/鼠/小鼠TGF-β1)

暂无内容