Human Kallikrein人类激肽释放酶HPKa 1303 说明书

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Enzyme Research 是一家拥有超过25年的酶研究的实验室,生产和开发多种用于基本凝血研究的多种酶和辅因子。在过去的十年Enzyme Research Laboratories为科学家参与止血和血栓形成的研究提供了宝贵支持。Enzyme Research通过不断追求产品的zui高品质,赢得了世界各地凝血研究实验室的信任。

Human Kallikrein

 

HPKa 1303             Human Kallikrein

Activation of Prekallikrein with Factor α-XIIa produces the enzymatically active Kallikrein. Kallikrein is a serine protease which consists of a heavy chain (Mr 52kD) and light chains (Mr either 36 or 33 kD) linked by disulfide bridges. Kallikrein possesses enzymatic activity toward Factor XII, HK, Plasminogen, Factors XI, IX, and VII, prorenin and the complement system. After activation, the activating enzyme Factor XIIa is removed by affinity chromatography. Human Kallikrein purity is determined by SDS-PAGE and shows complete reduction upon incubation with 2-mercaptoethanol.

Buffer composition = 4 mM Sodium Acetate-HCl/0.15 M NaCl/pH 5.3
*Extinction Coefficient (1%) = 11.7
Molecular Weight = ~86,000 daltons

 

 

 

Enzyme HPKa 1303

 

Enzyme Research Laboratories公司是一家致力于提供高纯度凝血因子相关产品的生物高科技公司,供应的产品包括纯化的人/牛血浆蛋白(包括多种凝血因子)、重组蛋白、Immune Depleted Plasmas、凝血/血栓研究相关抗体。产品广泛应用于生物技术、生物制药、医院及研究所的科研等众多领域。作为该领域的行业先进者,Enzyme Research Laboratories在近十年间为止血及血栓症研究提供了的产品支持。除了成熟的产品线外,Enzyme Research Laboratories公司凭借多年的研发和鉴定经验,还提供蛋白/多肽测序、多肽合成、寡核苷酸合成、氨基酸谱分析等定制研究服务。

Human Kallikrein

 

Human Kallikrein
Catalog Number: HPKa 1303
Size: 1.0 mg

Activation of Prekallikrein with Factor α-XIIa produces the enzymatically active Kallikrein. Kallikrein is a serine protease which consists of a heavy chain (Mr 52kD) and light chains (Mr either 36 or 33 kD) linked by disulfide bridges. Kallikrein possesses enzymatic activity toward Factor XII, HK, Plasminogen, Factors XI, IX, and VII, prorenin and the complement system. After activation, the activating enzyme Factor XIIa is removed by affinity chromatography. Human Kallikrein purity is determined by SDS-PAGE and shows complete reduction upon incubation with 2-mercaptoethanol.

Buffer composition = 4 mM Sodium Acetate-HCl/0.15 M NaCl/pH 5.3
Extinction Coefficient (1%) = 11.7
Molecular Weight = ~86,000 daltons

Human Kallikrein Sample Certificate of Analysis

人类激肽释放酶

 

货号

品名

CAS

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品牌

HPKa 1303 Human Kallikrein 4-6周到货 7422 1.0 mg Enzyme research2018

 

人类激肽释放酶
目录编号:HPKa 1303 
大小:1.0 mg

用因子α-XIIa激活前激肽释放酶产生酶活性激肽释放酶。激肽释放酶是一种丝氨酸蛋白酶,由重链(Mr 52kD)和轻链(Mr 36或33 kD)组成,通过二硫键连接。激肽释放酶具有对因子XII,HK,纤溶酶原,因子XI,IX和VII,前肾素和补体系统的酶活性。活化后,通过亲和层析除去活化酶因子XIIa。通过SDS-PAGE测定人激肽释放酶纯度,并显示在与2-巯基乙醇温育后*还原。

缓冲液组成= 4 mM乙酸钠-HCl / 0.15 M NaCl / pH 5.3 
消光系数(1%)= 11.7 
分子量= ~86,000道尔顿

人类激肽释放酶样品  分析证书

 

 

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