Hoechst 33258染色液
产品编号: C1018
产品包装:50ml
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Hoechst 33258染色液(C1018)
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价格: ¥ 349.00
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| 产品编号 | 产品名称 | 产品包装 | 产品价格 |
| C1017 | Hoechst 33258染色液 | 10ml | 107.00元 |
| C1018 | Hoechst 33258染色液 | 50ml | 349.00元 |
Hoechst 33258，也称bisBenzimide H 33258或HOE 33258。分子式为C25H24N6O·3HCl，分子量为533.88，CAS
Number 23491-45-4。
Hoechst 33258是一种可以穿透细胞膜的蓝色荧光染料，对细胞的毒性较低。
Hoechst 33258染色常用于细胞凋亡检测，染色后用荧光显微镜观察或流式细胞仪检测。Hoechst 33258也常用于普通的细胞核染色，或常规的DNA染色。
Hoechst 33258的最大激发波长为346nm，最大发射波长为460nm；Hoechst 33258和双链DNA结合后，最大激发波长为352nm，最大发射波长为461nm。
本Hoechst 33258染色液可直接用于固定细胞或组织的细胞核染色，也可直接用于活细胞或组织的细胞核染色。
包装清单：
| 产品编号 | 产品名称 | 包装 |
| C1018 | Hoechst 33258染色液 | 50ml |
| — | 说明书 | 1份 |
保存条件：
-20℃避光保存，一年有效。
注意事项：
本Hoechst 33258 染色液的浓度经过碧云天的优化，确保可以满足各种常规染色的需要。如需使用特定浓度的Hoechst 33258，请选购碧云天的Hoechst 33258(C1011)。如需染色活细胞或培养的组织，请选购碧云天的Hoechst 33342活细胞染色液(100X) (C1027、C1028或C1029)，效果更佳。
荧光染料都存在淬灭的问题，建议染色后尽量当天完成检测。活细胞或组织染色后宜立即观察。
为减缓荧光淬灭可以使用抗荧光淬灭封片液。抗荧光淬灭封片液(P0126)可以向碧云天订购。
Hoechst 33258对人体有害，请注意适当防护。
本产品仅限于专业人员的科学研究用，不得用于临床诊断或治疗，不得用于食品或药品，不得存放于普通住宅内。
为了您的安全和健康，请穿实验服并戴一次性手套操作。
使用说明：
1. 对于固定的细胞或组织：
a. 对于细胞或组织样品，固定后，适当洗涤去除固定剂。随后如果需要进行免疫荧光染色，则先进行免疫荧光染色，染色完毕后再按后续步骤进行Hoechst 33258染色。如果不需要进行其它染色，则直接进行后续的Hoechst 33258染色。
b. 对于贴壁细胞或组织切片，加入少量Hoechst 33258染色液，覆盖住样品即可。对于悬浮细胞，至少加入待染色样品体积3倍的染色液，混匀。室温放置3-5分钟。
c. 吸除Hoechst 33258染色液，用TBST、PBS或生理盐水洗涤2-3次，每次3-5分钟。
d. 直接在荧光显微镜下观察或封片后荧光显微镜下观察。细胞发生凋亡时，会看到凋亡细胞的细胞核呈致密浓染，或呈碎块状致密浓染。
2. 对于活细胞或培养的组织：
a. 加入适当量Hoechst 33258染色液，必须充分覆盖住待染色的样品，通常对于六孔板一个孔需加入1ml染色液，对于96孔板一个孔需加入100微升染色液。
b. 在适宜于细胞培养的温度培养20-30分钟。弃染色液，用PBS或培养液洗涤2-3次即可进行荧光检测。细胞发生凋亡时，在荧光显微镜下观察会看到凋亡细胞的细胞核呈致密浓染，或呈碎块状致密浓染。
相关产品：
| 产品编号 | 产品名称 | 包装 |
| C1002 | DAPI | 5mg/ml×0.2ml |
| C1005 | DAPI染色液 | 10ml |
| C1006 | DAPI染色液 | 50ml |
| C1011 | Hoechst 33258 | 10mg |
| C1017 | Hoechst 33258染色液 | 10ml |
| C1018 | Hoechst 33258染色液 | 50ml |
| C1022 | Hoechst 33342 | 10mg |
| C1025 | Hoechst 33342染色液 | 10ml |
| C1026 | Hoechst 33342染色液 | 50ml |
| C1027 | Hoechst 33342活细胞染色液(100X) | 0.1ml |
| C1028 | Hoechst 33342活细胞染色液(100X) | 0.5ml |
| C1029 | Hoechst 33342活细胞染色液(100X) | 3ml |
相关产品请点击如下按钮：
荧光染色
细胞凋亡
细胞凋亡荧光探针
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The effect ofwhole body low dose radiation on apoptosis of mice leukemia cell.
《潍坊医学院学报》 . 2011 Oct;39(10):1018-29.
76. Muhammad Khan,Bin Zheng,Fei Yi,Azhar Rasul,Zhuyi Gu.
Pseudolaric Acid B Induces Caspase-Dependent and Caspase-Independent Apoptosis in U87 Glioblastoma Cells.
Evidence-Based Complementary and Alternative Medicine ,2012;2012:957568. (IF 1.984)
77. Yuan XH, Lu CL, Yao N, An LS, Yang BQ, Zhang CL, Ma X.
Arsenic induced progesterone production in a caspase-3-dependent manner and changed redoxstatus in preovulatory granulosa cells.
J Cell Physiol . 2012 Jan;227(1):194-203. (IF 5.546)
78. Wang JJ, Li YF, Jin YY, Wang X, Chen TX.
Effects of Epstein-Barr virus on the development of dendritic cells derived from cord bloodmonocytes: an essential role for apoptosis.
Braz J Infect Dis . 2012 Jan-Feb;16(1):19-26. (IF 1.971)
79. Wang PH, Wan DH, Pang LR, Gu ZH, Qiu W, Weng SP, Yu XQ, He JG.
Molecular cloning, characterization and expression analysis of the tumor necrosis factor (TNF) superfamily gene, TNF receptor superfamily gene and lipopolysaccharide-induced TNF-α factor (LITAF) gene from Litopenaeus vannamei.
Dev Comp Immunol .2012 Jan;36(1):39-50. (IF 3.192)
80. Song J, Wang M, Huang H, Luo X, Deng F, Wang H, Hu Z.
Functional studies of per os infectivity factor 3 of Helicoverpa armigera nucleopolyhedrovirus.
J Gen Virol . 2012 Feb;93(Pt 2):374-82. (IF 3.376)
81. Li XJ, Zhu CD, Yu W, Wang P, Chen FF, Xia XY, Luo B.
Overexpression of Id3 induces apoptosis of A549 human lung adenocarcinoma cells.
CELL PROLIFERAT . 2012 Feb;45(1):1-8. (IF 5.753)
82. Zhou P, Li H, Wang H, Wang LF, Shi Z.
Bat severe acute respiratory syndrome-like coronavirus ORF3b homologues display differentinterferon antagonist activities.
J Gen Virol . 2012 Feb;93(Pt 2):275-81. (IF 3.376)
83. Wang PH, Liang JP, Gu ZH, Wan DH, Weng SP, Yu XQ, He JG.
Molecular cloning, characterization and expression analysis of two novel Tolls (LvToll2 and LvToll3) and three putative Spätzle-like Toll ligands (LvSpz1-3) from Litopenaeus vannamei.
Dev Comp Immunol . 2012 Feb;36(2):359-71. (IF 3.192)
84. Chen YH, Zhao L, Jia XT, Li XY, Li CZ, Yan H, Weng SP, He JG.
Isolation and characterization of cDNAs encoding Ars2 and Pasha homologues, two components of the RNAinterference pathway in Litopenaeus vannamei.
FISH SHELLFISH IMMUN . 2012 Feb;32(2):373-80. (IF 3.298)
85. Li SZ,Li YH,Li JL,Liu C,Yin W,Zhao QX,Lin Z,Ji H and Yang HM.
Construction of pECFP-C1-CIRP and its effect on cold-induced apoptosis in mouse NIH/3T3 cells.
AFR J BIOTECHNOL .2012 Mar;11(21):4938-48. (IF 0.573)
86. Zhang L, Ruan J, Yan L, Li W, Wu Y, Tao L, Zhang F, Zheng S, Wang A, Lu Y.
Xanthatin induces cell cycle arrest at G2/M checkpoint and apoptosis via disrupting NF-κB pathwayin A549 non-small-cell lung cancer cells.
Molecules . 2012 Mar 26;17(4):3736-50. (IF 3.267)
87. Shi W, Nie D, Jin G, Chen W, Xia L, Wu X, Su X, Xu X, Ni L, Zhang X, Zhang X, Chen J.
BDNF blended chitosan scaffolds for human umbilical cord MSC transplants in traumatic braininjury therapy.
Biomaterials . 2012 Apr;33(11):3119-26. (IF 10.317)
88. Wu C, Deng W, Deng L, Cao L, Qin B, Li S, Wang Y, Pei R, Yang D, Lu M, Chen X.
Amino acid substitutions at positions 122 and 145 of hepatitis B virus surface antigen (HBsAg)determine the antigenicity and immunogenicity of HBsAg and influence in vivo HBsAg clearance.
J Virol . 2012 Apr;86(8):4658-69. 1. (IF 4.501)
89. Tao L, Chen J, Zheng Z, Meng J, Zhang Z, Chen Y, Luo H, Li H, Chen Z, Hu Q, Wang H.
H5N1 influenza virus-like particles produced by transient expression in mammalian cells induce humoral andcellular immune responses in mice.
Can J Microbiol . 2012 Apr;58(4):391-401. (IF 1.793)
90. He D, Ma X, Chen Y, Cai Y, Ru X, Bruce IC, Xia Q, Shi G, Jin J.
Luteolin inhibits pyrogallol-induced apoptosis through the extracellular signal-regulated kinasesignaling pathway.
FEBS J . 2012 May;279(10):1834-43. (IF 4.392)
91. Liu M, Yang S, Jin L, Hu D, Wu Z, Yang S.
Chemical Constituents of the Ethyl Acetate Extract of Belamcanda chinensis (L.) DCRoots and Their Antitumor Activities.
Molecules . 2012 May 24;17(5):6156-69. (IF 3.267)
92. Yinghui Dong1, Hanhan Yao2, Zhihua Lin1,Dongli Zhu.
The effects of sperm–egg ratios on polyspermy in the blood clam,Tegillarca granosa.
Aquaculture Research .2012 Jun;43(1):44–52. (IF 1.502)
93. Zeng F, Ni E, Wang S, Lv S, Cao C, Zhang H, Lv H, Chen X, Yan J, Luo F.
A Monoclonal Antibody Against the Catalytic Domain of PTP1B.
HYBRIDOMA (Larchmt). 2012 Jun;31(3):209-13. (IF 0.244)
94. Jiang C, Zhang S, Liu H, Zeng Q, Xia T, Chen Y, Kuang G, Zhao G, Wu X, Zhang X, Wang A.
The role of the IRE1 pathway in PBDE-47-induced toxicity in human neuroblastoma SH-SY5Y cellsin vitro.
Toxicol Lett . 2012 Jun 20;211(3):325-33. (IF 3.569)
95. Tang W, Zhang Y, Qian C, Yuan Z.
Induction and mechanism of apoptosis by hydroxycamptothecin in human Tenon’s capsulefibroblasts.
INVEST OPHTH VIS SCI . 2012 Jul 24;53(8):4874-80. (IF 3.47)
96. Yang S, Ma J, Xiao J, Lv X, Li X, Yang H, Liu Y, Feng S, Zhang Y.
Arctigenin Anti-Tumor Activity in Bladder Cancer T24 Cell Line Through Induction of Cell-CycleArrest and Apoptosis.
ANAT REC .2012 Aug;295(8):1260-6. (IF 1.634)
97. Liu GY, Yang J, Dai F, Yan WJ, Wang Q, Li XZ, Ding DJ, Cao XY, Zhou B.
CuII ions and the stilbene-chroman hybrid with a catechol moiety synergistically induced DNA damage, and cell cycle arrest and apoptosis of HepG2 cells: an interesting acid/base-promoted prooxidant reaction.
Chemistry . 2012 Aug 27;18(35):11100-6.
98. Zhong Q, Zhou Y, Ye W, Cai T, Zhang X, Deng DY.
Hypoxia-Inducible Factor 1-α-AA-Modified Bone Marrow Stem Cells Protect PC12 Cells fromHypoxia-Induced Apoptosis, Partially Through VEGF/PI3K/Akt/FoxO1 Pathway.
Stem Cells Dev .2012 Sep 20;21(14):2703-17. (IF 3.082)
99. Su W, Chen Y, Zeng W, Liu W, Sun H.
Involvement of Wnt signaling in the injury of murine mesenchymal stem cells exposed to X-radiation.
Int J Radiat Biol . 2012 Sep;88(9):635-41. (IF 2.368)
100. Jiang QH, Liu L, Shen JW, Peel S, Yang GL, Zhao SF, He FM.
Influence of multilayer rhBMP-2 DNA coating on the proliferation and differentiation of MC3T3-E1cells seeded on roughed titanium surface.
J Biomed Mater Res A . 2012 Oct;100(10):2766-74. (IF 3.525)
101. Zhao P, Han T, Guo JJ, Zhu SL, Wang J, Ao F, Jing MZ, She YL, Wu ZH, Ye LB.
HCV NS4B induces apoptosis through the mitochondrial death pathway.
Virus Res . 2012 Oct;169(1):1-7. (IF 2.934)
102. Di S, Tian Z, Qian A, Li J, Wu J, Wang Z, Zhang D, Yin D, Brandi ML, Shang P.
Large gradient high magnetic field affects FLG29.1 cells differentiation to form osteoclast-like cells.
Int J Radiat Biol . 2012 Nov;88(11):806-13. (IF 2.368)
103. Zhang S, Yan H, Li CZ, Chen YH, Yuan FH, Chen YG, Weng SP, He JG.
Identification and function of leucine-rich repeat flightless-I-interacting protein 2 (LRRFIP2) in Litopenaeusvannamei.
PLoS One . 2013;8(2):e57456. (IF 2.74)
104. Ye Y, Li Z, Xing D.
Nitric oxide promotes MPK6-mediated caspase-3-like activation in cadmium-induced Arabidopsisthaliana programmed cell death.
Plant Cell Environ .2013 Jan;36(1):1-15. (IF 6.362)
105. Yu W, Sheng M, Xu R, Yu J, Cui K, Tong J, Shi L, Ren H, Du H.
Berberine protects human renal proximal tubular cells from hypoxia/reoxygenation injury via inhibitingendoplasmic reticulum and mitochondrial stress pathways.
J Transl Med . 2013 Jan 29;11:24. (IF 4.124)
106. Zhou L, Huang J, Wang H, Luo J, Zeng L, Xiong K, Chen D.
Expression of Glutamate and GABA during the Process of Rat Retinal Synaptic Plasticity Induced by Acute HighIntraocular Pressure.
ACTA HISTOCHEM CYTOC . 2013 Feb 28;46(1):11-8. (IF 1.39)
107. Yang S, Zhao Q, Xiang H, Liu M, Zhang Q, Xue W, Song B, Yang S.
Antiproliferative activity and apoptosis-inducing mechanism of constituents from Toona sinensis on humancancer cells.
CANCER CELL INT t. 2013 Feb 9;13(1):12. (IF 4.175)
108. Zhang JF, Zhang JG, Kuai XL, Zhang H, Jiang W, Ding WF, Li ZL, Zhu HJ, Mao ZB.
Reactivation of the homeotic tumor suppressor gene CDX2 by 5-aza-2′-deoxycytidine-induced demethylation inhibits cell proliferation and induces caspase-independent apoptosis in gastric cancer cells.
Exp Ther Med . 2013 Mar;5(3):735-741. (IF 1.785)
109. Tang XP, Tang GD, Fang CY, Liang ZH, Zhang LY.
Effects of ginsenoside Rh2 on growth and migration of pancreatic cancer cells.
WORLD J GASTROENTERO . 2013 Mar 14;19(10):1582-92. (IF 3.665)
110. Huang J, Zhou L, Wang H, Luo J, Zeng L, Xiong K, Chen D.
Distribution of thrombospondins and their neuronal receptor α2δ1 in the rat retina.
Exp Eye Res . 2013 Jun;111:36-49. (IF 3.011)
111. Zhu D, Yu H, He H, Ding J, Tang J, Cao D, Hao L.
Spironolactone inhibits apoptosis in rat mesangial cells under hyperglycaemic conditions via the Wnt signallingpathway.
Mol Cell Biochem . 2013 Aug;380(1-2):185-93. (IF 2.795)
112. Yang YH, Chen K, Li B, Chen JW, Zheng XF, Wang YR, Jiang SD, Jiang LS.
Estradiol inhibits osteoblast apoptosis via promotion of autophagy through the ER-ERK-mTOR pathway.
Apoptosis . 2013 Nov;18(11):1363-75. (IF 4.543)
113. Li W, Zhao XL, Shang SQ, Shen HQ, Chen X.>
Dual Inhibition of Cdc7 and Cdk9 by PHA-767491 Suppresses Hepatocarcinoma Synergistically with 5-Fluorouracil.
CURR CANCER DRUG TAR .2015;15(3):196-204. (IF 2.912)
114. Jia G, Wang Q, Wang R, Deng D, Xue L, Shao N, Zhang Y, Xia X, Zhi F, Yang Y.
Tubeimoside-1 induces glioma apoptosis through regulation of Bax/Bcl-2 and the ROS/Cytochrome C/Caspase-3 pathway.
ONCOTARGETS THER . 2015 Jan 30;8:303-11. (IF 3.337)
115. Wu T, Wang S, Wu J, Lin Z, Sui X, Xu X, Shimizu N, Chen B, Wang X.
Icaritin induces lytic cytotoxicity in extranodal NK/T-cell lymphoma.
J EXP CLIN CANC RES . 2015 Feb 15;34:17. (IF 7.068)
116. Jiang L, Wang L, Chen L, Cai GH, Ren QY, Chen JZ, Shi HJ, Xie YH.
As2O3 induces apoptosis in human hepatocellular carcinoma HepG2 cells through a ROS-mediated mitochondrial pathway and activation of caspases.
Int J Clin Exp Med . 2015 Feb 15;8(2):2190-6. (IF 0.166)
117. Li RL, Huang JJ, Shi YQ, Hu A, Lu ZY, Weng L, Wang SQ, Han YP, Zhang L, Hao CN, Duan JL.
Pulsed electromagnetic field improves postnatal neovascularization in response to hindlimb ischemia.
Am J Transl Res . 2015 Mar 15;7(3):430-44. (IF 3.375)
118. Zhang K, Wang X, Wang C, Zheng H, Li T, Xiao S, Wang M, Fei C, Zhang L, Xue F.
Investigation of quinocetone-induced mitochondrial damage and apoptosis in HepG2 cells and compared with its metabolites.
ENVIRON TOXICOL CHEM .2015 Mar;39(2):555-67. (IF 3.152)
119. Wu D, Hu Q, Liu X, Pan L, Xiong Q, Zhu YZ.
Hydrogen sulfide protects against apoptosis under oxidative stress through SIRT1 pathway in H9c2 cardiomyocytes.
NITRIC OXIDE-BIOL CH . 2015 Apr 30;46:204-12. (IF 3.311)
120. Wang X, Jiang P, Wang P, Yang CS, Wang X, Feng Q.
EGCG Enhances Cisplatin Sensitivity by Regulating Expression of the Copper and Cisplatin Influx Transporter CTR1 in Ovary Cancer.
PLoS One . 2015 Apr 30;10(4):e0125402. (IF 2.74)
121. Peng X, Zhuang DD, Guo QS.
Induction of S phase arrest and apoptosis by ethyl acetate extract from Tetrastigma hemsleyanum in human hepatoma HepG2 cells.
TUMOR BIOL . 2015 Apr;36(4):2541-50. (IF 3.65)
122. Xu L, Liu JH, Zhang J, Zhang N, Wang ZH.
Blockade of autophagy aggravates endoplasmic reticulum stress and improves Paclitaxel cytotoxicity in human cervical cancer cells.
Cancer Res Treat . 2015 Apr;47(2):313-21. (IF 3.761)
123. Fu X, Liu Y, Zhuang C, Liu L, Cai Z, Huang W.
Synthetic artificial microRNAs targeting UCA1-MALAT1 or c-Myc inhibit malignant phenotypes of bladder cancer cells T24 and 5637.
Mol Biosyst . 2015 May;11(5):1285-9. (IF 3.336)
124. Dai JQ, Huang YG, He AN.
Dihydromethysticin kavalactone induces apoptosis in osteosarcoma cells through modulation of PI3K/Akt pathway, disruption of mitochondrial membrane potential and inducing cell cycle arrest.
INT J CLIN EXP PATHO . 2015 May 1;8(5):4356-66. (IF 0.252)
125. Luo Q, Liu X, Zheng Y, Zhao Y, Zhu J, Zou L.
Ephrin-B2 mediates trophoblast-dependent maternal spiral artery remodeling in first trimester.
Placenta . 2015 May;36(5):567-74. (IF 3.177)
126. Lu J, Cao Y, Cheng K, Xu B, Wang T, Yang Q, Yang Q, Feng X, Xia Q.
Berberine regulates neurite outgrowth through AMPK-dependent pathways by lowering energy status.
Exp Cell Res . 2015 Jun 10;334(2):194-206. (IF 3.383)
127. Yan L, Wang C, Lin B, Liu J, Liu D, Hou R, Wang Y, Gao L, Zhang S, Iwamori M.
Lewis y enhances CAM-DR in ovarian cancer cells by activating the FAK signaling pathway and upregulating Bcl-2/Bcl-XL expression.
Biochimie . 2015 Jun;113:17-25. (IF 3.413)
128. Yang JA, Li JQ, Shao LM, Yang Q, Liu BH, Wu TF, Wu P, Yi W, Chen QX.
Puerarin inhibits proliferation and induces apoptosis in human glioblastoma cell lines.
Int J Clin Exp Med . 2015 Jun 15;8(6):10132-42. (IF 0.166)
129. Wu L, Dai J, Zhao X, Chen Y, Wang G, Li K.
Chloroquine enhances replication of influenza A virus A/WSN/33 (H1N1) in dose-, time-, and MOI-dependent manners in human lung epithelial cells A549.
J Med Virol . 2015 Jul;87(7):1096-103. (IF 2.021)
130. Zhuang CL, Fu X, Liu L, Liu YC, Huang WR, Cai ZM.
Synthetic miRNA sponges driven by mutant hTERT promoter selectively inhibit the progression of bladder cancer.
TUMOR BIOL . 2015 Jul;36(7):5157-63. (IF 3.65)
131. Zeng X, Tan X.
Epigallocatechin-3-gallate and zinc provide anti-apoptotic protection against hypoxia/reoxygenation injury in H9c2 rat cardiac myoblast cells.
Mol Med Rep . 2015 Aug;12(2):1850-6. (IF 2.1)
132. Zuo N, Zheng X, Liu H, Ma X.
Fenofibrate, a PPARα agonist, protect proximal tubular cells from albumin-bound fatty acids induced apoptosis via the activation of NF-kB.
INT J CLIN EXP PATHO . 2015 Sep 1;8(9):10653-61. (IF 0.252)
133. Wang LY, Li X, Han YZ.
Neuroprotection by epigallo catechin gallate against bupivacaine anesthesia induced toxicity involves modulation of PI3/Akt/PTEN signalling in N2a and SH-SY5Y cells.
Int J Clin Exp Med . 2015 Sep 15;8(9):15065-75. (IF 0.166)
134. Dong M, Lu Y, Zou Z, Yang H.
Monoacylglycerol lipase inhibitor protects primary cultured neurons against homocysteine-induced impairments in rat caudate nucleus through COX-2 signaling.
Life Sci . 2015 Oct 1;138:64-71. (IF 3.647)
135. Wang W, Yan M, Ji Q, Lu J, Ji Y, Ji J.
Suberoylanilide hydroxamic acid suppresses hepatic stellate cells activation by HMGB1 dependent reduction of NF-κB1.
PeerJ . 2015 Nov 3;3:e1362. (IF 2.379)
136. Peng PA, Wang L, Ma Q, Xin Y, Zhang O, Han HY, Liu XL, Ji QW, Zhou YJ, Zhao YX.
Valsartan protects HK-2 cells from contrast media-induced apoptosis by inhibiting endoplasmic reticulum stress.
Cell Biol Int .2015 Dec;39(12):1408–17. (IF 2.571)
137. Huang L, Du B, Gong Y, Xu H, Lu J, Si X.
Effects of Exogenous Interleukin-9 on the Growth, Proliferation and Activity of Interstitial Cells of CajalCultured in vitro.
Digestion . 2016;94(3):154-165. (IF 2.692)
138. Han H, Yang J, Fei S, Liu Z, Zhu S, Dong Q, Gao Z, Wang S, Zhang J.
Protective effect of carbachol postconditioning on hypoxia/reoxygenation-induced injury in human gastric epithelial cells.
Life Sci . 2016 Jan;144:234–42. (IF 3.647)
139. Zhao H, Ma T, Fan B, Yang L, Han C, Luo J, Kong L.
Protective effect of trans-δ-viniferin against high glucose-induced oxidative stress in human umbilical vein endothelial cells through the SIRT1 pathway.
FREE RADICAL RES . 2016 Jan;50(1):68-83. (IF 2.839)
140. Wu C, Hu Y, Fan L, Wang H, Sun Z, Deng S, Liu Y, Hu C.
Ctenopharyngodon idella PKZ facilitates cell apoptosis through phosphorylating eIF2α.
Mol Immunol . 2016 Jan;69:13-23. (IF 3.641)
141. Pan C, Hu YF, Song J, Yi HS, Wang L, Yang YY, Wang YP, Zhang M, Pan MH, Lu C.
Effects of 10-hydroxycamptothecin on intrinsic mitochondrial pathway in silkworm BmN-SWU1 cells.
PESTIC BIOCHEM PHYS . 2016 Feb;127:15-20. (IF 2.751)
142. Wang W, Long L, Wang L, Tan C, Fei X, Chen L, Huang Q, Liang Z.
Knockdown of Cathepsin L promotes radiosensitivity of glioma stem cells both in vivo and in vitro.
Cancer Lett . 2016 Feb 28;371(2):274-84. (IF 7.36)
143. Luo P, Zhang WF, Qian ZX, Xiao LF, Wang H, Zhu TT, Li F, Hu CP, Zhang Z.
MiR-590-5p-meidated LOX-1 upregulation promotes Angiotensin II-induced endothelial cell apoptosis.
BIOCHEM BIOPH RES CO . 2016 Mar 18;471(4):402-8. (IF 2.985)
144. Nie GH, Luo L, Duan HF, Li XQ, Yin MJ, Li Z, Zhang W.
GALNT7, a target of miR-494, participates in the oncogenesis of nasopharyngeal carcinoma.
TUMOR BIOL .2016 Apr;37(4):4559–67. (IF 3.65)
145. Jiang Q, Liu Y, Duan D, Gou M, Wang H, Wang J, Li Q, Xiao R.
Anti-angiogenic activities of CRBGP from buccal glands of lampreys (Lampetra japonica).
Biochimie . April 2016 Apr;123:7–19. (IF 3.413)
146. Yu J, Xu H, Shen X, Jiang H.
Ghrelin protects MES23.5 cells against rotenone via inhibiting mitochondrial dysfunction and apoptosis.
Neuropeptides . 2016 Apr;56:69-74. (IF 2.411)
147. Xing SF, Jang M, Wang YR, Piao XL.
A new dammarane-type saponin from Gynostemma pentaphyllum induces apoptosis in A549 humanlung carcinoma cells.
Bioorg Med Chem Lett . 2016 Apr 1;26(7):1754-9. (IF 2.572)
148. Li J, Zhang Y, Luan H, Chen X, Han Y, Wang C.
l-carnitine protects human hepatocytes from oxidative stress-induced toxicity through Akt-mediatedactivation of Nrf2 signaling pathway.
CAN J PHYSIOL PHARM . 2016 May;94(5):517-25. (IF 1.946)
149. Liang Y, Ji J, Lin Y, He Y, Liu J.
The Ganglioside GM-1 Inhibits Bupivacaine-Induced Neurotoxicity in Mouse Neuroblastoma Neuro2aCells.
Cell Biochem Funct . 2016 Aug;34(6):455-62. (IF 2.632)
150. Jiang JM, Wang L, Gu HF, Wu K, Xiao F, Chen Y, Guo RM, Tang XQ.
Arecoline Induces Neurotoxicity to PC12 Cells: Involvement in ER Stress and Disturbance ofEndogenous H2S Generation.
Neurochem Res . 2016 Aug;41(8):2140-8. (IF 3.038)
151. Li J, Li J, Aipire A, Gao L, Huo S, Luo J, Zhang F.
Phenylethanoid Glycosides from Cistanche tubulosa Inhibits the Growth of B16-F10 Cells both in Vitroand in Vivo by Induction of Apoptosis via Mitochondria-dependent Pathway.
J Cancer .2016 Sep 12;7(13):1877-1887. (IF 3.565)
152. Liu X, Bi Y.
Y-27632 Increases Sensitivity of PANC-1 Cells to EGCG in Regulating Cell Proliferation and Migration.
MED SCI MONITOR . 2016 Oct 3;22:3529-3534. (IF 1.918)
153. Ji BL, Xia LP, Zhou FX, Mao GZ, Xu LX.
Aconitine induces cell apoptosis in human pancreatic cancer via NF-κB signaling pathway.
EUR REV MED PHARMACO . 2016 Dec;20(23):4955-4964. (IF 3.024)
154. Yu N, Xiong Y, Wang C.
Bu-Zhong-Yi-Qi Decoction,the Water Extract of Chinese Traditional Herbal Medicine, EnhancesCisplatin Cytotoxicity in A549/DDP Cells through Induction of Apoptosis and Autophagy.
Biomed Res Int . 2017;2017:3692797. (IF 2.276)
155. Zhu J, Jiang Y, Yang X, Wang S, Xie C, Li X, Li Y, Chen Y, Wang X, Meng Y, Zhu M, Wu R, Huang C, Ma X, Geng S, Wu J, Zhong C.
Wnt/β-catenin pathway mediates (-)-Epigallocatechin-3-gallate (EGCG) inhibition of lung cancer stemcells.
BIOCHEM BIOPH RES CO . 2017 Jan 1;482(1):15-21. (IF 2.985)
156. Chen L, Wang L, Yan J, Ma C, Lu J, Chen G, Chen S, Su F, Wang W, Su X.
131I-labeled monoclonal antibody targeting neuropilin receptor type-2 for tumor SPECT imaging.
Int J Oncol . 2017 Feb;50(2):649-659. (IF 3.899)
157. Jiang Q, Li Q, Han J, Gou M, Zheng Y, Li B, Xiao R, Wang J.
rLj-RGD3 induces apoptosis via the mitochondrial-dependent pathway and inhibits adhesion, migrationand invasion of human HeyA8 cells via FAK pathway.
J PATHOL . 2017 Mar;96:652-668. (IF 5.979)
158. Luo H, Yang S, Hong D, Xue W, Xie P.
Synthesis andin vitro antitumor activity of (1E,4E)-1-aryl-5-(2-((quinazolin-4-yl)oxy)phenyl)-1,4-pentadien-3-one derivatives.
Chem Cent J . 2017 Mar 15;11:23. (IF 2.493)
159. Liu F, Li X, Yue H, Ji J, You M, Ding L, Fan H, Hou Y.
TLR-Induced SMPD3 Defects Enhance Inflammatory Response of B Cell and Macrophage in the Pathogenesis of SLE.
Scand J Immunol . 2017 Nov;86(5):377-388. (IF 2.717)
160. Shangguan WJ, Zhang YH, Li ZC, Tang LM, Shao J, Li H.
Naringin inhibits vascularendothelialcell apoptosis viaendoplasmicreticulumstress andmitochondrial mediated pathways and promotes intraosseous angiogenesis in ovariectomized rats.
Int J Mol Med . 2017 Dec;40(6):1741-1749. (IF 3.098)
161. Liu D,You P,Luo Y,Yang M,Liu Y
Galangin Induces Apoptosis in MCF-7 Human Breast Cancer Cells Through Mitochondrial Pathway and Phosphatidylinositol 3-Kinase/Akt Inhibition.
Pharmacology . 2018;102(1-2):58-66. (IF 1.625)
162. Lu K,Rui G,Liu F,Yang L,Deng X,Shi S,Li Q
14-3-3ε is a nuclear matrix protein, and its altered expression and localization are associated with curcumin-induced apoptosis of MG-63 cells.
Oncol Lett . 2018 Jan;15(1):338-346. (IF 2.311)
163. Huang L,Huang K,Ning H
Hispidulin prevents sevoflurane- Induced memory dysfunction in aged rats.
Biomed Pharmacother. 2018 Jan;97:412-422. (IF 4.545)
164. Li L,Li W,Wang C,Yan X,Wang Y,Niu C,Zhang X,Li M,Tian H,Yao C,Jin H,Han F,Xu D,Han W,Li D,Cui J
Adoptive transfer of natural killer cells in combination with chemotherapy improves outcomes of patients with locally advanced colon carcinoma.
Cytotherapy. 2018 Jan;20(1):134-148. (IF 4.218)
165. Zou WW,Xu SP
Galangin inhibits the cell progression and induces cell apoptosis through activating PTEN and Caspase-3 pathways in retinoblastoma.
Biomed Pharmacother. 2018 Jan;97:851-863. (IF 4.545)
166. Xu H,Wang Z,Sun Z,Ni Y,Zheng L
GATA4 protects against hyperglycemia‑induced endothelial dysfunction by regulating NOX4 transcription.
Mol Med Rep. 2018 Jan;17(1):1485-1492. (IF 2.1)
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MAT SCI ENG C-MATER . 2018 Feb 1;83:195-201. (IF 5.88)
168. Duan D,Wang H,Zhou R,Jiang Q,Xiao R
The PR-1 domain accounts for the anti-angiogenic activity of a cysteine-rich secretory protein member from the buccal glands of Lampetra japonica.
Int J Biol Macromol. 2018 Feb;107(Pt B):2102-2112. (IF 5.162)
169. Meng PP,Li Z,Wang SY,Zhou WW,Samiullah M,Chen N,Luo FH,Wu T,Yan JH
Preparation, Purification, and Identification of a Monoclonal Antibody Against the C-Terminal Domain of Semaphorin3F.
Monoclon Antib Immunodiagn Immunother. 2018 Feb;37(1):52-58.
170. Zhou RP,Ni WL,Dai BB,Wu XS,Wang ZS,Xie YY,Wang ZQ,Yang WJ,Ge JF,Hu W,Chen FH
ASIC2a overexpression enhances the protective effect of PcTx1 and APETx2 against acidosis-induced articular chondrocyte apoptosis and cytotoxicity.
Gene. 2018 Feb 5;642:230-240. (IF 2.984)
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Asperosaponin VI promotes angiogenesis and accelerates wound healing in rats via up-regulating HIF-1α/VEGF signaling.
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172. Zhang J,Zhang Z,Shu B,Cui G,Zhong G
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Int J Mol Sci . 2018 Mar 11;19(3). pii: E811. (IF 4.556)
173. Wang C,Mao C,Lou Y,Xu J,Wang Q,Zhang Z,Tang Q,Zhang X,Xu H,Feng Y
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J Cell Mol Med. 2018 Mar;22(3):1583-1600. (IF 4.486)
174. Chen W,Yu Y,Yang N,Zhu J,Li K,Li R,Su W,Luo L,Hu L,Chen G,Deng H
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175. Zhang X,Zhang M,Xiao B,Jiao W,Zhang S,Zhang X
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Oncol Rep. 2018 Mar;39(3):1423-1431. (IF 3.417)
176. Zhang B,Cui Y,Wang L,Zhao L,Hou C,Zeng Q,Zhang Z,Yu J,Zhao Y,Nie J,Chen X,Wang A,Liu H
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Toxicol Lett. 2018 Mar 1;284:129-135. (IF 3.569)
177. Huang RZ,Huang XC,Zhang B,Jia HY,Liao ZX,Wang HS
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Phytomedicine. 2018 Mar 1;41:33-44. (IF 4.268)
178. Wang W,Qing X,Wang B,Ma K,Wei Y,Shao Z
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179. Jiang W,Guo M,Gong M,Chen L,Bi Y,Zhang Y,Shi Y,Qu P,Liu Y,Chen J,Li T
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Acta Pharmacol Sin . 2018 Apr;39(4):642-648. (IF 5.064)
182. Du X,Zhu Y,Peng Z,Cui Y,Zhang Q,Shi Z,Guan Y,Sha X,Shen T,Yang Y,Li X,Wang Z,Li X,Liu G
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183. Li A,Gu Y,Li X,Sun H,Zha H,Xie J,Zhao J,Huang M,Chen L,Peng Q,Zhang Y,Weng Y,Zhou L
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184. Zhang B,Zhang Y,Liu B,Fang L,Li Y,Meng S
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Contrast Media Mol Imaging. 2018 Apr 10;2018:8303609.
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Food Funct. 2018 Apr 25;9(4):2374-2385. (IF 4.171)
186. Yuan M,Ning M,Wei P,Hao W,Jing Y,Gu W,Wang W,Meng Q
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FISH SHELLFISH IMMUN. 2018 May;76:21-26. (IF 3.298)
187. Yang W,Wu F,Luo T,Zhang Y
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Exp Ther Med. 2018 May;15(5):4213-4222. (IF 1.785)
188. Shi H,Yu F,Mao Y,Ju Q,Wu Y,Bai W,Wang P,Xu R,Jiang M,Shi J
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189. Yang B,Yan P,Yang GZ,Cao HL,Wang F,Li B
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190. Dai S,Zhang T,Zhang Y,Wang H,Deng F
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191. Zhang X,Zhang S,Sun Q,Jiao W,Yan Y,Zhang X
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Fitoterapia. 2018 Oct;130:234-240. (IF 2.527)
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Gene. 2018 Nov 30;677:266-272. (IF 2.984)
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Eur J Pharmacol. 2018 Nov 5;838:157-169. (IF 3.263)
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Life Sci. 2019 Jan 1;216:259-270. (IF 3.647)
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Biol Pharm Bull. 2019 Sep 1;42(9):1491-1499. (IF 1.863)
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Front Oncol. 2019 Sep 4;9:853. (IF 4.848)
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J Med Virol. 2020 Jan;92(1):96-106.;doi: 10.1002/jmv.25579. (IF 2.021)
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Front Cell Dev Biol. 2020 Feb 14;8:56.;doi: 10.3389/fcell.2020.00056. (IF 5.201)
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Salidroside enhances proliferation and maintains phenotype of articular chondrocytes for autologous chondrocyte implantation (ACI) via TGF-β/Smad3 Signal
Biomed Pharmacother. 2020 Feb;122:109388.;doi: 10.1016/j.biopha.2019.109388. (IF 4.545)
230. Yue Geng,Yeting Chen,Wei Sun,Yingmin Gu,Yongjie Zhang,Mei Li,Jiajun Xie,Xuesong Tian
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EVID-BASED COMPL ALT. 2020 Mar 16;2020:3495836.;doi: 10.1155/2020/3495836. (IF 1.813)
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Melatonin Promotes the Proliferation of Chicken Sertoli Cells by Activating the ERK/Inhibin Alpha Subunit Signaling Pathway
Molecules. 2020 Mar 9;25(5):1230.;doi: 10.3390/molecules25051230. (IF 3.267)
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Acta Pharmacol Sin. 2020 Apr;41(4):508-515.;doi: 10.1038/s41401-020-0378-6. (IF 5.064)
234. Wangkai Xie,Chao Chen,Zheng Han,Jingjing Huang,Xin Liu,Hongjun Chen,Teming Zhang,Sian Chen,Chenbin Chen,Mingdong Lu,Xian Shen,Xiangyang Xue
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MOL CARCINOGEN. 2020 Apr;59(4):339-352.;doi: 10.1002/mc.23158. (IF 3.825)
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HNGF6A Inhibits Oxidative Stress-Induced MC3T3-E1 Cell Apoptosis and Osteoblast Phenotype Inhibition by Targeting Circ_0001843/miR-214 Pathway
CALCIFIED TISSUE INT. 2020 May;106(5):518-532.;doi: 10.1007/s00223-020-00660-z. (IF 3.423)
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Sesamin promotes angiogenesis and accelerates wound healing in rats via alleviates TBHP-induced apoptosis in human umbilical vein endothelial cells
BIOSCI BIOTECH BIOCH. 2020 May;84(5):887-897.;doi: 10.1080/09168451.2020.1715200. (IF 1.516)
237. Shengdong Wang,Hengyuan Li,Shi Chen,Zenan Wang,Yuhong Yao,Tao Chen,Zhaoming Ye,Peng Lin
Andrographolide induces apoptosis in human osteosarcoma cells via the ROS/JNK pathway
Int J Oncol. 2020 Jun;56(6):1417-1428.;doi: 10.3892/ijo.2020.5032. (IF 3.899)
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Potential Role of SLC5A8 Expression in the Etiology of Subacute Ruminal Acidosis
Front Vet Sci. 2020 Jul 30;7:394.;doi: 10.3389/fvets.2020.00394. (IF 2.245)
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MED SCI MONITOR. 2020 Jul 31;26:e924507.;doi: 10.12659/MSM.924507. (IF 1.918)
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Cr(VI)-induced overactive mitophagy contributes to mitochondrial loss and cytotoxicity in L02 hepatocytes
Biochem J. 2020 Jul 31;477(14):2607-2619.;doi: 10.1042/BCJ20200262. (IF 4.097)
241. Mei Yang,Qingyuan Gui,Jinlei Ma,Lei Qi,Bijun Bao,Yida Huang
Upconversion nanotubes with tunable fluorescence properties based on Gd 2 O 2 S:Ln 3+ (Ln 3+ = Yb 3+, Er 3+) and derivatives for photodynamic therapy
IET Nanobiotechnol. 2020 Jul;14(5):347-356.;doi: 10.1049/iet-nbt.2019.0376. (IF 1.859)
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The neuroprotective effect of apigenin against OGD/R injury in rat hippocampal neurons
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Astilbin protects against cerebral ischaemia/reperfusion injury by inhibiting cellular apoptosis and ROS-NLRP3 inflammasome axis activation
Int Immunopharmacol. 2020 Jul;84:106571.;doi: 10.1016/j.intimp.2020.106571. (IF 3.943)
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Mol Med Rep. 2020 Aug;22(2):1420-1428.;doi: 10.3892/mmr.2020.11217. (IF 2.1)
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Nicotine induces cardiac toxicity through blocking mitophagic clearance in young adult rat
Life Sci. 2020 Sep 15;257:118084.;doi: 10.1016/j.lfs.2020.118084. (IF 3.647)
247. Minyi Tian,Xianghuan Wu,Tingya Lu,Xiaoge Zhao,Feng Wei,Guodong Deng,Ying Zhou
Phytochemical Analysis, Antioxidant, Antibacterial, Cytotoxic, and Enzyme Inhibitory Activities of Hedychium flavum Rhizome
Front Pharmacol. 2020 Sep 17;11:572659.;doi: 10.3389/fphar.2020.572659. (IF 4.225)
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Anti-proliferative effects of diterpenoids from Sagittaria trifolia L. tubers on colon cancer cells by targeting the NF-κB pathway
Food Funct. 2020 Sep 23;11(9):7717-7726.;doi: 10.1039/d0fo00228c. (IF 4.171)
249. Patrick Wilson,Christopher Stamper,Haley Dugan,Lei Li,Nicholas Asby,Peter Halfmann,Jenna Guthmiller,Nai-Ying Zheng,Min Huang,Olivia Stovicek,Jiaolong Wang,Maria Lucia Madariaga,Kumaran Shanmugarajah,Maud Jansen,Fatima Amanat,Isabelle Stewart,Siriruk Changrob,Henry Utset,Jun Huang,Christopher Nelson,Ya-Nan Dai,Paige Hall,Robert Jedrzejczak,Andrzej Joachimiak,Florian Krammer,Daved Fremont,Yoshihiro Kawaoka
Distinct B cell subsets give rise to antigen-specific antibody responses against SARS-CoV-2
Res Sq. 2020 Sep 25;rs.3.rs-80476.;doi: 10.21203/rs.3.rs-80476/v1.
250. Ying Shi,Qing Li,Feng Sun,Chenyue Zhu,Sainan Ma,Di Qin,Qingwei Li,Tiesong Li
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FISH SHELLFISH IMMUN. 2020 Sep;104:613-621.;doi: 10.1016/j.fsi.2020.06.037. (IF 3.298)
251. Juncheng Liu,Fang Wang,Zebin Weng,Xiaonan Sui,Yong Fang,Xiaozhi Tang,Xinchun Shen
Soybean-derived miRNAs specifically inhibit proliferation and stimulate apoptosis of human colonic Caco-2 cancer cells but not normal mucosal cells in culture
Genomics. 2020 Sep;112(5):2949-2958.;doi: 10.1016/j.ygeno.2020.05.011. (IF 6.205)
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PDB-1 from Potentilla discolor Bunge induces apoptosis and autophagy by downregulating the PI3K/Akt/mTOR signaling pathway in A549 cells
Biomed Pharmacother. 2020 Sep;129:110378.;doi: 10.1016/j.biopha.2020.110378. (IF 4.545)
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Mol Med Rep. 2020 Sep;22(3):2415-2423.;doi: 10.3892/mmr.2020.11325. (IF 2.1)
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EGCG Upregulates UCP 3 Levels to Protect MIN 6 Pancreatic Islet Cells from Interleukin-1β-Induced Apoptosis
DRUG DES DEV THER. 2020 Oct 13;14:4251-4261.;doi: 10.2147/DDDT.S270345. (IF 3.216)
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Thorac Cancer. 2020 Oct;11(10):2993-2997.;doi: 10.1111/1759-7714.13643. (IF 2.61)
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Baculovirus Surface Display of Zika Virus Envelope Protein Protects against Virus Challenge in Mouse Model
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257. Xing Fang,TingFei Tan,BeiBei Gao,YingLi Zhao,TingTing Liu,Quan Xia
Germacrone Regulates HBXIP-Mediated Cell Cycle, Apoptosis and Promotes the Formation of Autophagosomes to Inhibit the Proliferation of Gastric Cancer Cells
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258. Xiangshang Xu,Li Li,Xiaolan Li,Deding Tao,Peng Zhang,Jianping Gong
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259. Bing Hao,Anjie Shi,Xiuhong Li,Jia Li,Zhibin Liu,Hongfeng Yuan
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260. Yating Wen,Hongliang Chen,Fangzhen Luo,Lanhua Zhao,Mingyi Shu,Shengmei Su,Yuqi Zhao,Qiulin Huang,Zhongyu Li
Chlamydia trachomatis Plasmid Protein pORF5 Up-Regulates ZFAS1 to Promote Host Cell Survival via MAPK/p38 Pathway
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261. Shilai Li,Quanlin Qin,Daqing Luo,Wenhui Pan,Yuqing Wei,Yansong Xu,Jijin Zhu,Liming Shang
Hesperidin ameliorates liver ischemia/reperfusion injury via activation of the Akt pathway
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262. Xiaoyu Dong,Zili He,Guangheng Xiang,Leyi Cai,Zhenjiang Xu,Cong Mao,Yongzeng Feng
Paeoniflorin promotes angiogenesis and tissue regeneration in a full-thickness cutaneous wound model through the PI3K/AKT pathway
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263. Xiaobo Hu,Cong Hu,Jun Liu,Zhuan Wu,Tingting Duan,Zhaohui Cao
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264. Xiangxun Chen,Mengxi Zhou,Wenjie Fan,Mingwei Yang,Lin Yang
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265. Xiujun Deng,Xinghuan Liang,Haiyan Yang,Zhenxing Huang,Xuemei Huang,Chunfeng Liang,Yaqi Kuang,Yingfen Qin,Faquan Lin,Zuojie Luo
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266. Lili Hou,Xin Yuan,Guannan Le,Ziman Lin,Fang Gan,Haolei Li,Kehe Huang
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