血管性血友病因子(von Willebrand Factor, vWF),是由第12号染色体的短臂所编码的糖蛋白。vWF可同时与胶原纤维和血小板结合,当血管破裂时大量血小板以vWF为中介,粘附在胶原纤维上,形成血栓,得以止血。在正常的生理条件下,绝大部份由内皮细胞合成,其余则由巨噬细胞生成。前者产生后多储存在W-P小体(Weibel-Palade body,WPB)内, 后者则储存在血小板的颗粒中。它与一系列心血管疾病如动脉粥样硬化、急性冠状动脉综合征、心房颤动等均关系密切,vWF是一种重要的血浆成分。vWF在止血过程中主要由两种作用:①与血小板膜GPⅠb-Ⅸ复合物及内皮下胶原结合,介导血小板在血管损伤部位的黏附;②与因子Ⅷ结合,作为载体具有稳定因子Ⅷ的作用。此外,vWF也能结合GPⅡb-Ⅲa,参与血小板的聚集过程。正常人血浆vWF浓度约为10mg/L。在内皮细胞受刺激或损伤以及集体处于应激状态时,血浆vWF水平升高。vWF及某些止血与纤溶成分都是血栓性疾病的独立危险因素。相反,当vWF基因发生缺失、插入点突变、剪切点替换或提前形成转录终止信号时,导致血浆vWF量有显著减低或有质的缺陷,不能完成其正常的止血功能时,即为vWD。
von Willebrand Factor (vWF)相关对照?
货号 | 品名 | 包装 | 价格 | 品牌 |
5450312 | Technozym vWF:CBA Control Set 2×0,5 ml | CE | 2650.98 | Technoclone |
5450212 | Technozym vWF:Ag Control Set 2×0,5 ml | CE | 2650.98 | Technoclone |
CEV20302 | Human vWF ELISA Kit Low (Negative) Reference Control | 1100 | AssayPro | |
CEV20301 | Human vWF ELISA Kit High (Positive) Reference Control | 900 |
AssayPro
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von Willebrand Factor (vWF)抗体?
货号 | 品名 | 包装 | 价格 | 品牌 |
SARTW-IG | Sheep anti rat vWF – von Willebrand Factor purified IgG | 5 mg | 2975 | affinitybiologicals |
SARTW-HRP | Sheep anti rat vWF – von Willebrand Factor peroxidase conjugated IgG | 0.2 mg | 3519 | affinitybiologicals |
SACWF-IG | Sheep anti canine vWF – von Willebrand Factor purified IgG | 5 mg | 2839 | affinitybiologicals |
SACWF-HRP | Sheep anti canine vWF – von Willebrand Factor peroxidase conjugated IgG | 0.2 mg | 3349 | affinitybiologicals |
GAVWF-IG | Goat anti human vWF – von Willebrand Factor purified IgG | 2.5 mg | 2091 | affinitybiologicals |
GAVWF-HRP | Goat anti human vWF – von Willebrand Factor peroxidase conjugated IgG | 0.15 mg | 3519 | affinitybiologicals |
GAVWF-APFTC | Goat anti human vWF – von Willebrand Factor affinity purified, FITC conjugated IgG | 0.1 mg | 3519 | affinitybiologicals |
GAVWF-APBIO | Goat anti human vWF – von Willebrand Factor affinity purified, Biotinylated IgG | 0.1 mg | 3519 | affinitybiologicals |
GAVWF-AP | Goat anti human vWF – von Willebrand Factor affinity purified IgG | 0.5 mg | 4794 | affinitybiologicals |
PAHVWF-S | Sheep anti-Human vWF | 1×1 mg | 1310.4 | Haematologic Technologies |
PAHVWF-S | Sheep anti-Human vWF | 1×5 mg | 4499.04 | Haematologic Technologies |
ADGESvWF8 | murine Mab against human vWF | 500 µg | 5575 | American Diagnostica Inc |
SARTW-IG | Anti-Rat von Willebrand Factor (RvWF)sheep, purified IgG, | 5 mg | 2975 | Enzyme Research2016 |
SARTW-HRP | Anti-Rat von Willebrand Factor (RvWF)sheep, perox-conj. IgG, | 0.2 mg | 3519 | Enzyme Research2016 |
GAVWF-HRP | Anti-human von Willebrand Factor (vWF)goat, perox-conj. IgG, | 0.15 mg | 3519 | Enzyme Research2016 |
GAVWF-APFTC | Anti-human von Willebrand Factor (vWF)goat, AP-FITC | 0.1 mg | 3519 | Enzyme Research2016 |
GAVWF-AP | Anti-human von Willebrand Factor (vWF)goat, affinity purified IgG, | 0.5 mg | 4794 | Enzyme Research2016 |
GAVWF-IG | Anti-human von Willebrand Factor (vWF)goat, affinity adsorbed IgG, | 2.5 mg | 2600 | Enzyme Research2016 |
SACWF-IG | Anti-Canine von Willebrand Factor (CvWF)sheep, purified IgG, | 5 mg | 2839 | Enzyme Research2016 |
SACWF-HRP | Anti-Canine von Willebrand Factor (CvWF)sheep, perox-conj. IgG, | 0.2 mg | 3349 | Enzyme Research2016 |
von Willebrand Factor (vWF)
货号 | 品名 | 包装 | 价格 | 品牌 |
PV10212 | Von Willebrand factor (vWF), Human | 100 ug | 4900 | AssayPro |
ADG206 | Von Willebrand factor deficient human plasma | 1 mL | 2100 | American Diagnostica Inc |
2042 | von Willebrand Factor (vWF), human, fVIII free, frozen solution, dry-ice shipment | 100 µg | 9444 | American Diagnostica Inc |
HCVWF-0190 | Human von Willebrand Factor | 1×100 µg | 4700.37204 | Haematologic Technologies |
HCVWF-0190 | Human von Willebrand Factor | 5×100 µg | 21257.964 | Haematologic Technologies |
HCVWF-0190 | Human von Willebrand Factor | 5×1 mg | 188487.2808 | Haematologic Technologies |
HCVWF-0190 | Human von Willebrand Factor | 10×1 mg | 371305.7712 | Haematologic Technologies |
HCVWF-0190 | Human von Willebrand Factor | 50×1 mg | 1669931.172 | Haematologic Technologies |
HCVWF-0190 | Human von Willebrand Factor | 100×1 mg | 3264278.472 | Haematologic Technologies |
HCVWF-0190 | Human von Willebrand Factor | 500×1 mg | 14703425.1 | Haematologic Technologies |
HCVWF-0191 | Human von Willebrand Factor (Factor VIII free) | 1×100 µg | 5621.55048 | Haematologic Technologies |
HCVWF-0191 | Human von Willebrand Factor (Factor VIII free) | 5×100 µg | 25391.457 | Haematologic Technologies |
HCVWF-0191 | Human von Willebrand Factor (Factor VIII free) | 5×1 mg | 226043.0172 | Haematologic Technologies |
HCVWF-0191 | Human von Willebrand Factor (Factor VIII free) | 10×1 mg | 445472.4456 | Haematologic Technologies |
HCVWF-0191 | Human von Willebrand Factor (Factor VIII free) | 50×1 mg | 2004153.606 | Haematologic Technologies |
HCVWF-0191 | Human von Willebrand Factor (Factor VIII free) | 100×1 mg | 3918551.364 | Haematologic Technologies |
HCVWF-0191 | Human von Willebrand Factor (Factor VIII free) | 500×1 mg | 17644110.12 | Haematologic Technologies |
von Willebrand Factor (vWF)缺乏血浆
货号 | 品名 | 包装 | 价格 | 品牌 |
DP150K | vWF Deficient Plasma | 6 x 1 mL | 2220 | hyphen biomed |
D203003 | Human vWF deficient plasma (Sodium Citrate) | 10 x 10 ml | 16000 | AssayPro |
D203002 | Human vWF deficient plasma (Sodium Citrate) | 10 ml | 1800 | AssayPro |
D203001 | Human vWF deficient plasma (Sodium Citrate) | 1 ml | 200 | AssayPro |
D203012 | Human vWF deficient plasma (Serum) | 10 x 10 ml | 16000 | AssayPro |
D203011 | Human vWF deficient plasma (Serum) | 10 ml | 1800 | AssayPro |
D203010 | Human vWF deficient plasma (Serum) | 1 ml | 200 | AssayPro |
D203009 | Human vWF deficient plasma (Heparin) | 10 x 10 ml | 16000 | AssayPro |
D203008 | Human vWF deficient plasma (Heparin) | 10 ml | 1800 | AssayPro |
D203007 | Human vWF deficient plasma (Heparin) | 1 ml | 200 | AssayPro |
D203006 | Human vWF deficient plasma (EDTA) | 10 x 10 ml | 16000 | AssayPro |
D203005 | Human vWF deficient plasma (EDTA) | 10 ml | 1800 | AssayPro |
D203004 | Human vWF deficient plasma (EDTA) | 1 ml | 200 | AssayPro |
VWF-DP | human von Willebrand Factor deficient plasma | 1ml | 163 | affinitybiologicals |
VWF-LDP | human von Willebrand Factor deficient plasma | 1ml | 183 | affinitybiologicals |
von Willebrand Factor (vWF)?试剂盒
货号 | 品名 | 包装 | 价格 | 品牌 |
RK038A | ZYMUTEST vWF:CBA | Kit of 96 tests | 5370 | hyphen biomed |
RK030A | ZYMUTEST vWF | Kit of 96 tests | 5790 | hyphen biomed |
von Willebrand Factor | von Willebrand Factor elisa kit | 5 plate | 7633 | Enzyme Research2016 |
5450321 | Technozym vWF:CBA ELISA Typ VI 96 T. | RUO | 10603.92 | Technoclone |
5450311 | Technozym vWF:CBA ELISA Typ I 96 T. | CE | 7906.02 | Technoclone |
5450301 | Technozym vWF:CBA ELISA 96 T. | CE | 7788.72 | Technoclone |
5450310 | Technozym vWF:CBA Calibration Set 5×0,5 ml | CE | 2791.74 | Technoclone |
5450201 | Technozym vWF:Ag ELISA 96 T. | CE | 7788.72 | Technoclone |
5450210 | Technozym vWF:Ag Calibration Set 5×0,5 ml | CE | 2791.74 | Technoclone |
ADG886 | IMUCLONE™ von Willebrand Factor-CB activity ELISA | 96 microwell plate | 10250 | American Diagnostica Inc |
828 | IMUBIND® vWF ELISA | 96 microwell plate | 8184 | American Diagnostica Inc |
885 | IMUBIND® vWF Activity ELISA | 96 microwell plate | 9756 | American Diagnostica Inc |
EV2030-7 | Human Von Willebrand Factor (VWF) ELISA Kit (WHO Standard calibrated controls included) | 96 well plate | 5600 | AssayPro |
EV2030-1 | Human Von Willebrand Factor (VWF) ELISA Kit | 96 well plate | 4760 | AssayPro |
VWF-EIA | von Willebrand Factor | 5 plates | 7633 | affinitybiologicals |
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