小鼠抗Myc-tag单克隆抗体 小鼠单克隆抗体|Myc-tag,Mouse mAb

小鼠抗Myc-tag单克隆抗体 小鼠单克隆抗体|Myc-tag,Mouse mAb

产品说明书

FAQ

COA

已发表文献

产品信息

 

产品名称

产品编号

规格

Myc-tag , Mouse mAb

30601ES20

20 μL

30601ES60

100 μL

 

产品简介

 

c-Myc 蛋白是一种位于细胞核内的转录因子,参与细胞增殖、分化和凋亡等生理过程。研究表明,在胃癌、乳腺癌、

结肠癌和宫颈癌等许多肿瘤组织或细胞中,c-Myc 蛋白的表达量要明显高于正常组织和细胞中的表达量。Myc 标签(EQKLISEEDL)是来自 c-Myc 蛋白的一段多肽,由于分子量很小,不会影响融合蛋白的生物特性,广泛用于检测细菌、酵母菌、昆虫和哺乳动物细胞等系统中融合蛋白的表达。Myc 标签可以放在 C 端或 N 端,Myc 融合蛋白可通过偶联 Myc 标签抗体到二乙烯砜活化的琼脂糖上而进行亲和纯化,但 c-Myc 融合蛋白的低 pH 洗脱条件往往会降低蛋白质的活力,因此c-Myc 标签系统多应用于检测但很少用于纯化。本抗体可用于检测带 Myc 标签的融合蛋白及天然 c-Myc 蛋白。

 

产品应用

 

建议稀释浓度:WB:1:1000-1:10000; IP: 1/500;

 

产品信息

 

产品类型(Product Type)

Mouse mAb

纯化方式(Purification method)

Affinity Purified

免疫原(Immunogen)

Monoclonal antibodies are produced by immunizing mouse with synthetic  peptide (EQKLISEEDL) coupled to KLH.

应用(Application)

WB,IP

储存缓冲液(Storage Buffer)

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

 

储存条件

 

-25~-15℃保存

 

注意事项

 

1. 避免反复冻融。

2. 本产品仅作科研用途

3. 为了您的安全和健康,请穿实验服并佩戴一次性手套操作。

 

Ver.CN20231009

小鼠抗Myc-tag单克隆抗体 小鼠单克隆抗体|Myc-tag,Mouse mAb

暂无内容

[1] Sun R, Guo Y, Li X, et al. PRRSV Non-Structural Proteins Orchestrate Porcine E3 Ubiquitin Ligase RNF122 to Promote PRRSV Proliferation. Viruses. 2022;14(2):424. Published 2022 Feb 18. doi:10.3390/v14020424(IF:5.048)
[2] Cheng Y, Zhu W, Ding C, et al. IRF7 Is Involved in Both STING and MAVS Mediating IFN-β Signaling in IRF3-Lacking Chickens. J Immunol. 2019;203(7):1930-1942. doi:10.4049/jimmunol.1900293(IF:4.718)
[3] Zhuang W, Yan Z. The S2-S3 Loop of Kv7.4 Channels Is Essential for Calmodulin Regulation of Channel Activation. Front Physiol. 2021;11:604134. Published 2021 Jan 20. doi:10.3389/fphys.2020.604134(IF:4.566)
[4] Wang X, Guo J, Che X, Jia R. PCBP1 inhibits the expression of oncogenic STAT3 isoform by targeting alternative splicing of STAT3 exon 23. Int J Biol Sci. 2019;15(6):1177-1186. Published 2019 May 7. doi:10.7150/ijbs.33103(IF:4.067)
[5] Che X, Liu M, Li D, Li Z, Guo J, Jia R. RAN and YBX1 are required for cell proliferation and IL-4 expression and linked to poor prognosis in oral squamous cell carcinoma. Exp Cell Res. 2021;406(2):112767. doi:10.1016/j.yexcr.2021.112767(IF:3.905)
[6] Liu Y, Cheng Y, Shan W, et al. Chicken interferon regulatory factor 1 (IRF1) involved in antiviral innate immunity via regulating IFN-β production. Dev Comp Immunol. 2018;88:77-82. doi:10.1016/j.dci.2018.07.003(IF:2.913)

产品信息

 

产品名称

产品编号

规格

Myc-tag , Mouse mAb

30601ES20

20 μL

30601ES60

100 μL

 

产品简介

 

c-Myc 蛋白是一种位于细胞核内的转录因子,参与细胞增殖、分化和凋亡等生理过程。研究表明,在胃癌、乳腺癌、

结肠癌和宫颈癌等许多肿瘤组织或细胞中,c-Myc 蛋白的表达量要明显高于正常组织和细胞中的表达量。Myc 标签(EQKLISEEDL)是来自 c-Myc 蛋白的一段多肽,由于分子量很小,不会影响融合蛋白的生物特性,广泛用于检测细菌、酵母菌、昆虫和哺乳动物细胞等系统中融合蛋白的表达。Myc 标签可以放在 C 端或 N 端,Myc 融合蛋白可通过偶联 Myc 标签抗体到二乙烯砜活化的琼脂糖上而进行亲和纯化,但 c-Myc 融合蛋白的低 pH 洗脱条件往往会降低蛋白质的活力,因此c-Myc 标签系统多应用于检测但很少用于纯化。本抗体可用于检测带 Myc 标签的融合蛋白及天然 c-Myc 蛋白。

 

产品应用

 

建议稀释浓度:WB:1:1000-1:10000; IP: 1/500;

 

产品信息

 

产品类型(Product Type)

Mouse mAb

纯化方式(Purification method)

Affinity Purified

免疫原(Immunogen)

Monoclonal antibodies are produced by immunizing mouse with synthetic  peptide (EQKLISEEDL) coupled to KLH.

应用(Application)

WB,IP

储存缓冲液(Storage Buffer)

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

 

储存条件

 

-25~-15℃保存

 

注意事项

 

1. 避免反复冻融。

2. 本产品仅作科研用途

3. 为了您的安全和健康,请穿实验服并佩戴一次性手套操作。

 

Ver.CN20231009

小鼠抗Myc-tag单克隆抗体 小鼠单克隆抗体|Myc-tag,Mouse mAb

暂无内容

[1] Sun R, Guo Y, Li X, et al. PRRSV Non-Structural Proteins Orchestrate Porcine E3 Ubiquitin Ligase RNF122 to Promote PRRSV Proliferation. Viruses. 2022;14(2):424. Published 2022 Feb 18. doi:10.3390/v14020424(IF:5.048)
[2] Cheng Y, Zhu W, Ding C, et al. IRF7 Is Involved in Both STING and MAVS Mediating IFN-β Signaling in IRF3-Lacking Chickens. J Immunol. 2019;203(7):1930-1942. doi:10.4049/jimmunol.1900293(IF:4.718)
[3] Zhuang W, Yan Z. The S2-S3 Loop of Kv7.4 Channels Is Essential for Calmodulin Regulation of Channel Activation. Front Physiol. 2021;11:604134. Published 2021 Jan 20. doi:10.3389/fphys.2020.604134(IF:4.566)
[4] Wang X, Guo J, Che X, Jia R. PCBP1 inhibits the expression of oncogenic STAT3 isoform by targeting alternative splicing of STAT3 exon 23. Int J Biol Sci. 2019;15(6):1177-1186. Published 2019 May 7. doi:10.7150/ijbs.33103(IF:4.067)
[5] Che X, Liu M, Li D, Li Z, Guo J, Jia R. RAN and YBX1 are required for cell proliferation and IL-4 expression and linked to poor prognosis in oral squamous cell carcinoma. Exp Cell Res. 2021;406(2):112767. doi:10.1016/j.yexcr.2021.112767(IF:3.905)
[6] Liu Y, Cheng Y, Shan W, et al. Chicken interferon regulatory factor 1 (IRF1) involved in antiviral innate immunity via regulating IFN-β production. Dev Comp Immunol. 2018;88:77-82. doi:10.1016/j.dci.2018.07.003(IF:2.913)